Functional Consequences of PDK4 Deficiency in Doberman Pinscher Fibroblasts

A splice site mutation in the canine pyruvate dehydrogenase kinase 4 (PDK4) gene has been shown to be associated with the development of dilated cardiomyopathy (DCM) in Doberman Pinchers (DPs). Subsequent studies have successfully demonstrated the use of dermal fibroblasts isolated from DPs as model...

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Detalles Bibliográficos
Autores principales: Bolfer, Luiz, Estrada, Amara H., Larkin, Chelsea, Conlon, Thomas J., Lourenco, Francisco, Taggart, Kathryn, Suzuki-Hatano, Silveli, Pacak, Christina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054397/
https://www.ncbi.nlm.nih.gov/pubmed/32127618
http://dx.doi.org/10.1038/s41598-020-60879-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054397/
https://www.ncbi.nlm.nih.gov/pubmed/32127618
http://dx.doi.org/10.1038/s41598-020-60879-6

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