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Collective effects of long-range DNA methylations predict gene expressions and estimate phenotypes in cancer
DNA methylation of various genomic regions has been found to be associated with gene expression in diverse biological contexts. However, most genome-wide studies have focused on the effect of (1) methylation in cis, not in trans and (2) a single CpG, not the collective effects of multiple CpGs, on g...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054398/ https://www.ncbi.nlm.nih.gov/pubmed/32127627 http://dx.doi.org/10.1038/s41598-020-60845-2 |