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Collective effects of long-range DNA methylations predict gene expressions and estimate phenotypes in cancer

DNA methylation of various genomic regions has been found to be associated with gene expression in diverse biological contexts. However, most genome-wide studies have focused on the effect of (1) methylation in cis, not in trans and (2) a single CpG, not the collective effects of multiple CpGs, on g...

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Detalles Bibliográficos
Autores principales: Kim, Soyeon, Park, Hyun Jung, Cui, Xiangqin, Zhi, Degui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054398/
https://www.ncbi.nlm.nih.gov/pubmed/32127627
http://dx.doi.org/10.1038/s41598-020-60845-2