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DKC1 enhances angiogenesis by promoting HIF-1α transcription and facilitates metastasis in colorectal cancer

BACKGROUND: Dyskeratosis congenita 1 (DKC1) is dysregulated in several cancers. However, the expression and function of DKC1 in colorectal cancer (CRC) is rarely reported. METHODS: Tissue microarrays (TAMs) including 411 cases of CRC tissues and corresponding paracancerous tissues were used to exami...

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Detalles Bibliográficos
Autores principales: Hou, Pingfu, Shi, Peicong, Jiang, Tao, Yin, Hang, Chu, Sufang, Shi, Meilin, Bai, Jin, Song, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054532/
https://www.ncbi.nlm.nih.gov/pubmed/31857720
http://dx.doi.org/10.1038/s41416-019-0695-z

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