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Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily

The rapid increase of multidrug resistance poses urgent threats to human health. Multidrug transporters prompt multidrug resistance by exporting different therapeutics across cell membranes, often by utilizing the H(+) electrochemical gradient. MdfA from Escherichia coli is a prototypical H(+) -depe...

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Detalles Bibliográficos
Autores principales:	Wu, Hsin-Hui, Symersky, Jindrich, Lu, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054563/ https://www.ncbi.nlm.nih.gov/pubmed/32127561 http://dx.doi.org/10.1038/s41598-020-60332-8

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