In vitro and in vivo pharmacokinetic characterization of LMT-28 as a novel small molecular interleukin-6 inhibitor

OBJECTIVE: Interleukin-6 (IL-6) is a T cell-derived B cell stimulating factor which plays an important role in inflammatory diseases. In this study, the pharmacokinetic properties of LMT-28 including physicochemical property, in vitro liver microsomal stability and an in vivo pharmacokinetic study u...

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Detalles Bibliográficos
Autores principales: Ahn, Sung-Hoon, Heo, Tae-Hwe, Jun, Hyun-Sik, Choi, Yongseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054612/
https://www.ncbi.nlm.nih.gov/pubmed/31480155
http://dx.doi.org/10.5713/ajas.19.0463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054612/
https://www.ncbi.nlm.nih.gov/pubmed/31480155
http://dx.doi.org/10.5713/ajas.19.0463

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