Sulfonamide-Based Azaheterocyclic Schiff Base Derivatives as Potential Carbonic Anhydrase Inhibitors: Synthesis, Cytotoxicity, and Enzyme Inhibitory Kinetics

A series of sulfonamide-bearing azaheterocyclic Schiff base derivatives 3(a-j) were synthesized as carbonic anhydrase inhibitors. The substituted benzene sulfonyl chlorides 1(a-d) were reacted with N(2)H(4) to get aromatic sulfonyl hydrazides 2(a-d). The intermediate hydrazides 2(a-d) were treated w...

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Detalles Bibliográficos
Autores principales: Abas, Mujahid, Rafique, Hummera, Shamas, Shazia, Roshan, Sadia, Ashraf, Zaman, Iqbal, Zafar, Raza, Hussain, Hassan, Mubashir, Afzal, Khurram, Rizvanov, Albert A., Asad, Muhammad Hassham Hassan Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054763/
https://www.ncbi.nlm.nih.gov/pubmed/32149140
http://dx.doi.org/10.1155/2020/8104107

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