Bcl-2 Proteins Regulate Mitophagy in Lipopolysaccharide-Induced Acute Lung Injury via PINK1/Parkin Signaling Pathway

Mitophagy is involved in sepsis-induced acute lung injury (ALI). Bcl-2 family proteins play an important role in mitochondrial homeostasis. However, whether targeting Bcl-2 proteins (Bcl-2 and Bad) could influence mitophagy in ALI remains unclear. In this study, lipopolysaccharide (LPS) was used to...

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Detalles Bibliográficos
Autores principales: Zhang, Zhihao, Chen, Zhugui, Liu, Ruimeng, Liang, Qingchun, Peng, Zhiyong, Yin, Shuang, Tang, Jing, Gong, Ting, Liu, Youtan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054785/
https://www.ncbi.nlm.nih.gov/pubmed/32148654
http://dx.doi.org/10.1155/2020/6579696

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