Using Extended-Release Injectable Aripiprazole for the Successful Treatment of Depressive Symptoms in Bipolar I Disorder

Extended-release injectable (ERI) aripiprazole is indicated for schizophrenia and maintenance monotherapy of bipolar I disorder. Clinical trials of aripiprazole failed to exhibit efficacy in the treatment of bipolar depression. It has been suggested that relatively high doses, rapid titration of dos...

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Detalles Bibliográficos
Autores principales: Kuo, Joseph, Lin, Shih-Ku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054796/
https://www.ncbi.nlm.nih.gov/pubmed/32148990
http://dx.doi.org/10.1155/2020/2615748
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author Kuo, Joseph
Lin, Shih-Ku
author_facet Kuo, Joseph
Lin, Shih-Ku
author_sort Kuo, Joseph
collection PubMed
description Extended-release injectable (ERI) aripiprazole is indicated for schizophrenia and maintenance monotherapy of bipolar I disorder. Clinical trials of aripiprazole failed to exhibit efficacy in the treatment of bipolar depression. It has been suggested that relatively high doses, rapid titration of dose, a high dropout rate, and a high placebo effect might be the reasons of its ineffectiveness. Here, we report a case of a 39-year-old woman with bipolar depression who was successfully treated with ERI aripiprazole.
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spelling pubmed-70547962020-03-06 Using Extended-Release Injectable Aripiprazole for the Successful Treatment of Depressive Symptoms in Bipolar I Disorder Kuo, Joseph Lin, Shih-Ku Case Rep Psychiatry Case Report Extended-release injectable (ERI) aripiprazole is indicated for schizophrenia and maintenance monotherapy of bipolar I disorder. Clinical trials of aripiprazole failed to exhibit efficacy in the treatment of bipolar depression. It has been suggested that relatively high doses, rapid titration of dose, a high dropout rate, and a high placebo effect might be the reasons of its ineffectiveness. Here, we report a case of a 39-year-old woman with bipolar depression who was successfully treated with ERI aripiprazole. Hindawi 2020-02-21 /pmc/articles/PMC7054796/ /pubmed/32148990 http://dx.doi.org/10.1155/2020/2615748 Text en Copyright © 2020 Joseph Kuo and Shih-Ku Lin. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kuo, Joseph
Lin, Shih-Ku
Using Extended-Release Injectable Aripiprazole for the Successful Treatment of Depressive Symptoms in Bipolar I Disorder
title Using Extended-Release Injectable Aripiprazole for the Successful Treatment of Depressive Symptoms in Bipolar I Disorder
title_full Using Extended-Release Injectable Aripiprazole for the Successful Treatment of Depressive Symptoms in Bipolar I Disorder
title_fullStr Using Extended-Release Injectable Aripiprazole for the Successful Treatment of Depressive Symptoms in Bipolar I Disorder
title_full_unstemmed Using Extended-Release Injectable Aripiprazole for the Successful Treatment of Depressive Symptoms in Bipolar I Disorder
title_short Using Extended-Release Injectable Aripiprazole for the Successful Treatment of Depressive Symptoms in Bipolar I Disorder
title_sort using extended-release injectable aripiprazole for the successful treatment of depressive symptoms in bipolar i disorder
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054796/
https://www.ncbi.nlm.nih.gov/pubmed/32148990
http://dx.doi.org/10.1155/2020/2615748
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