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The impact of reflexology and homeopathy added to conventional asthma treatment on markers of airway inflammation – a randomised study
BACKGROUND: Asthma is a common chronic airway disease associated with hyperresponsiveness and airway inflammation. Anti-inflammatory medication especially inhaled corticosteroids are important for control of airway inflammation, decrease of airway hyperresponsiveness and lung function variability, r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054942/ https://www.ncbi.nlm.nih.gov/pubmed/32166008 http://dx.doi.org/10.1080/20018525.2020.1726153 |
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author | Topcu, Ayfer Løkke, Anders Eriksen, Leila Nielsen, Lars Peter Dahl, Ronald |
author_facet | Topcu, Ayfer Løkke, Anders Eriksen, Leila Nielsen, Lars Peter Dahl, Ronald |
author_sort | Topcu, Ayfer |
collection | PubMed |
description | BACKGROUND: Asthma is a common chronic airway disease associated with hyperresponsiveness and airway inflammation. Anti-inflammatory medication especially inhaled corticosteroids are important for control of airway inflammation, decrease of airway hyperresponsiveness and lung function variability, reduce asthma symptoms, and improve lung function as well as quality of life. Most studies investigating the influence of complementary and alternative medicine (CAM) in asthma measure clinical effectiveness, but only few evaluate the impact on markers of airway inflammation. OBJECTIVE: The aim of this study was to investigate the effect of reflexology and homeopathy added to conventional treatment on different markers of airway inflammation in asthma. METHODS: Eighty-four patients with asthma were randomized to receive conventional treatment alone or conventional treatment with addition of homeopathy or reflexology in a single center, investigator blinded, controlled, one-year trial. During the study period, patients regularly consulted their general practitioner for evaluation and asthma treatment. At randomization, and after 6 and 12 months, methacholine challenge test and measurement of exhaled nitric oxide were performed. Blood samples were collected for eosinophil count and measurement of serum eosinophil cationic protein. RESULTS: No significant differences between groups for any of the inflammatory markers were demonstrated. Methacholine responsiveness improved in all three groups but improvements were not statistically significant within and between groups. CONCLUSIONS: This randomized controlled study of reflexology and homeopathy failed to show significant improvement on selected markers of inflammation and airway hyperresponsiveness in asthma. |
format | Online Article Text |
id | pubmed-7054942 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-70549422020-03-12 The impact of reflexology and homeopathy added to conventional asthma treatment on markers of airway inflammation – a randomised study Topcu, Ayfer Løkke, Anders Eriksen, Leila Nielsen, Lars Peter Dahl, Ronald Eur Clin Respir J Research Article BACKGROUND: Asthma is a common chronic airway disease associated with hyperresponsiveness and airway inflammation. Anti-inflammatory medication especially inhaled corticosteroids are important for control of airway inflammation, decrease of airway hyperresponsiveness and lung function variability, reduce asthma symptoms, and improve lung function as well as quality of life. Most studies investigating the influence of complementary and alternative medicine (CAM) in asthma measure clinical effectiveness, but only few evaluate the impact on markers of airway inflammation. OBJECTIVE: The aim of this study was to investigate the effect of reflexology and homeopathy added to conventional treatment on different markers of airway inflammation in asthma. METHODS: Eighty-four patients with asthma were randomized to receive conventional treatment alone or conventional treatment with addition of homeopathy or reflexology in a single center, investigator blinded, controlled, one-year trial. During the study period, patients regularly consulted their general practitioner for evaluation and asthma treatment. At randomization, and after 6 and 12 months, methacholine challenge test and measurement of exhaled nitric oxide were performed. Blood samples were collected for eosinophil count and measurement of serum eosinophil cationic protein. RESULTS: No significant differences between groups for any of the inflammatory markers were demonstrated. Methacholine responsiveness improved in all three groups but improvements were not statistically significant within and between groups. CONCLUSIONS: This randomized controlled study of reflexology and homeopathy failed to show significant improvement on selected markers of inflammation and airway hyperresponsiveness in asthma. Taylor & Francis 2020-02-26 /pmc/articles/PMC7054942/ /pubmed/32166008 http://dx.doi.org/10.1080/20018525.2020.1726153 Text en © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Topcu, Ayfer Løkke, Anders Eriksen, Leila Nielsen, Lars Peter Dahl, Ronald The impact of reflexology and homeopathy added to conventional asthma treatment on markers of airway inflammation – a randomised study |
title | The impact of reflexology and homeopathy added to conventional asthma treatment on markers of airway inflammation – a randomised study |
title_full | The impact of reflexology and homeopathy added to conventional asthma treatment on markers of airway inflammation – a randomised study |
title_fullStr | The impact of reflexology and homeopathy added to conventional asthma treatment on markers of airway inflammation – a randomised study |
title_full_unstemmed | The impact of reflexology and homeopathy added to conventional asthma treatment on markers of airway inflammation – a randomised study |
title_short | The impact of reflexology and homeopathy added to conventional asthma treatment on markers of airway inflammation – a randomised study |
title_sort | impact of reflexology and homeopathy added to conventional asthma treatment on markers of airway inflammation – a randomised study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054942/ https://www.ncbi.nlm.nih.gov/pubmed/32166008 http://dx.doi.org/10.1080/20018525.2020.1726153 |
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