Cargando…
Untangling the contribution of Haspin and Bub1 to Aurora B function during mitosis
Aurora B kinase is essential for faithful chromosome segregation during mitosis. During (pro)metaphase, Aurora B is concentrated at the inner centromere by the kinases Haspin and Bub1. However, how Haspin and Bub1 collaborate to control Aurora B activity at centromeres remains unclear. Here, we show...
Autores principales: | Hadders, Michael A., Hindriksen, Sanne, Truong, My Anh, Mhaskar, Aditya N., Wopken, J. Pepijn, Vromans, Martijn J.M., Lens, Susanne M.A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054988/ https://www.ncbi.nlm.nih.gov/pubmed/32027339 http://dx.doi.org/10.1083/jcb.201907087 |
Ejemplares similares
-
The Ins and Outs of Aurora B Inner Centromere Localization
por: Hindriksen, Sanne, et al.
Publicado: (2017) -
Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells
por: Hindriksen, Sanne, et al.
Publicado: (2017) -
The chromosomal passenger complex: guiding Aurora-B through mitosis
por: Vader, Gerben, et al.
Publicado: (2006) -
Shugoshin-1 Balances Aurora B Kinase Activity via PP2A to Promote Chromosome Bi-orientation
por: Meppelink, Amanda, et al.
Publicado: (2015) -
Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation
por: Wang, Fangwei, et al.
Publicado: (2012)