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Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane

The polyphosphoinositides (PPIn) are central regulatory lipids that direct membrane function in eukaryotic cells. Understanding how their synthesis is regulated is crucial to revealing these lipids’ role in health and disease. PPIn are derived from the major structural lipid, phosphatidylinositol (P...

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Detalles Bibliográficos
Autores principales: Zewe, James P., Miller, April M., Sangappa, Sahana, Wills, Rachel C., Goulden, Brady D., Hammond, Gerald R.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054989/
https://www.ncbi.nlm.nih.gov/pubmed/32211893
http://dx.doi.org/10.1083/jcb.201906127