Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation

The spindle assembly checkpoint (SAC) relies on the recruitment of Mad1-C-Mad2 to unattached kinetochores but also on its binding to Megator/Tpr at nuclear pore complexes (NPCs) during interphase. However, the molecular underpinnings controlling the spatiotemporal redistribution of Mad1-C-Mad2 as ce...

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Detalles Bibliográficos
Autores principales: Cunha-Silva, Sofia, Osswald, Mariana, Goemann, Jana, Barbosa, João, Santos, Luis M., Resende, Pedro, Bange, Tanja, Ferrás, Cristina, Sunkel, Claudio E., Conde, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054998/
https://www.ncbi.nlm.nih.gov/pubmed/31913420
http://dx.doi.org/10.1083/jcb.201906039

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