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TORC1 regulates vacuole membrane composition through ubiquitin- and ESCRT-dependent microautophagy
Cellular adaptation in response to nutrient limitation requires the induction of autophagy and lysosome biogenesis for the efficient recycling of macromolecules. Here, we discovered that starvation and TORC1 inactivation not only lead to the up-regulation of autophagy and vacuole proteins involved i...
Autores principales: | Yang, Xi, Zhang, Weichao, Wen, Xin, Bulinski, Patrick J., Chomchai, Dominic A., Arines, Felichi Mae, Liu, Yun-Yu, Sprenger, Simon, Teis, David, Klionsky, Daniel J., Li, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055007/ https://www.ncbi.nlm.nih.gov/pubmed/32045480 http://dx.doi.org/10.1083/jcb.201902127 |
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