MapPIng PI inside cells brings new light to polyphosphoinositide biology

It is unclear how phosphatidylinositol (PI), the precursor of polyphosphoinositides, is distributed within cell membranes. Pemberton et al. (2020. J. Cell. Biol. https://doi.org/10.1083/jcb.201906130) and Zewe et al. (2020. J. Cell. Biol. https://doi.org/10.1083/jcb.201906127) describe new approache...

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Detalles Bibliográficos
Autor principal: Drin, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055009/
https://www.ncbi.nlm.nih.gov/pubmed/32211897
http://dx.doi.org/10.1083/jcb.202001185
Descripción
Sumario:It is unclear how phosphatidylinositol (PI), the precursor of polyphosphoinositides, is distributed within cell membranes. Pemberton et al. (2020. J. Cell. Biol. https://doi.org/10.1083/jcb.201906130) and Zewe et al. (2020. J. Cell. Biol. https://doi.org/10.1083/jcb.201906127) describe new approaches to map the subcellular PI abundance and clarify how polyphosphoinositide metabolism relates to PI distribution.

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