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Analysis of multi-lineage gene expression dynamics during primordial germ cell induction from human induced pluripotent stem cells

BACKGROUND: In mammals, specification of primordial germ cells (PGCs) is established in the early postimplantation embryo. The bone morphogenetic protein (BMP)-SMAD and WNT3-β-catenin signaling initiate the gene regulatory network for PGC specification. The activation of SOX17-BLIMP1 axis is critic...

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Detalles Bibliográficos
Autores principales:	Fang, Fang, Li, Zili, Zhao, Qian, Xiong, Chengliang, Ni, Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055065/ https://www.ncbi.nlm.nih.gov/pubmed/32127035 http://dx.doi.org/10.1186/s13287-020-01620-y

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