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Non-CpG methylation biases bisulphite PCR towards low or unmethylated mitochondrial DNA: recommendations for the field

Mitochondrial DNA (mtDNA) is a circular genome of 16 kb that is present in multiple copies in mitochondria. mtDNA codes for genes that contribute to mitochondrial structure and function. A long-standing question has asked whether mtDNA is epigenetically regulated similarly to the nuclear genome. Rec...

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Detalles Bibliográficos
Autores principales:	Morris, Margaret J, Hesson, Luke B, Youngson, Neil A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Perspectives
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055202/ https://www.ncbi.nlm.nih.gov/pubmed/32154030 http://dx.doi.org/10.1093/eep/dvaa001

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