Cargando…
Selective Targeting of Virus Replication by Proton Pump Inhibitors
Two proton pump inhibitors, tenatoprazole and esomeprazole, were previously shown to inhibit HIV-1 egress by blocking the interaction between Tsg101, a member of the ESCRT-I complex, and ubiquitin. Here, we deepen our understanding of prazole budding inhibition by studying a range of viruses in the...
Autores principales: | Watanabe, Susan M., Ehrlich, Lorna S., Strickland, Madeleine, Li, Xiaofan, Soloveva, Veronica, Goff, Arthur J., Stauft, Charles B., Bhaduri-McIntosh, Sumita, Tjandra, Nico, Carter, Carol |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055211/ https://www.ncbi.nlm.nih.gov/pubmed/32132561 http://dx.doi.org/10.1038/s41598-020-60544-y |
Ejemplares similares
-
Inflammasome, the Constitutive Heterochromatin Machinery, and Replication of an Oncogenic Herpesvirus
por: Bhaduri-McIntosh, Sumita, et al.
Publicado: (2021) -
Chloroquine triggers Epstein-Barr virus replication through phosphorylation of KAP1/TRIM28 in Burkitt lymphoma cells
por: Li, Xiaofan, et al.
Publicado: (2017) -
RNA Binding Suppresses Tsg101 Recognition of Ub-Modified Gag and Facilitates Recruitment to the Plasma Membrane
por: Watanabe, Susan M., et al.
Publicado: (2020) -
A Central Role for STAT3 in Gammaherpesvirus-Life Cycle and -Diseases
por: Li, Xiaofan, et al.
Publicado: (2016) -
Novel Tsg101 Binding Partners Regulate Viral L Domain Trafficking
por: Strickland, Madeleine, et al.
Publicado: (2021)