Cargando…
High-Throughput Screening to Predict Chemical-Assay Interference
The U.S. federal consortium on toxicology in the 21(st) century (Tox21) produces quantitative, high-throughput screening (HTS) data on thousands of chemicals across a wide range of assays covering critical biological targets and cellular pathways. Many of these assays, and those used in other in vit...
Autores principales: | Borrel, Alexandre, Huang, Ruili, Sakamuru, Srilatha, Xia, Menghang, Simeonov, Anton, Mansouri, Kamel, Houck, Keith A., Judson, Richard S., Kleinstreuer, Nicole C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055224/ https://www.ncbi.nlm.nih.gov/pubmed/32132587 http://dx.doi.org/10.1038/s41598-020-60747-3 |
Ejemplares similares
-
High-Throughput Chemical Screening and Structure-Based Models to Predict hERG Inhibition
por: Krishna, Shagun, et al.
Publicado: (2022) -
Selecting a minimal set of androgen receptor assays for screening chemicals
por: Judson, Richard, et al.
Publicado: (2020) -
Use of Tox21 Screening Data to Evaluate the COVID-19 Drug Candidates for Their Potential Toxic Effects and Related Pathways
por: Sakamuru, Srilatha, et al.
Publicado: (2022) -
Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics
por: Zhu, Hu, et al.
Publicado: (2021) -
Identification of Compounds That Inhibit Estrogen-Related Receptor Alpha Signaling Using High-Throughput Screening Assays
por: Lynch, Caitlin, et al.
Publicado: (2019)