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High-Throughput Screening to Predict Chemical-Assay Interference

The U.S. federal consortium on toxicology in the 21(st) century (Tox21) produces quantitative, high-throughput screening (HTS) data on thousands of chemicals across a wide range of assays covering critical biological targets and cellular pathways. Many of these assays, and those used in other in vit...

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Detalles Bibliográficos
Autores principales: Borrel, Alexandre, Huang, Ruili, Sakamuru, Srilatha, Xia, Menghang, Simeonov, Anton, Mansouri, Kamel, Houck, Keith A., Judson, Richard S., Kleinstreuer, Nicole C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055224/
https://www.ncbi.nlm.nih.gov/pubmed/32132587
http://dx.doi.org/10.1038/s41598-020-60747-3

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