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A novel α-fetoprotein-derived helper T-lymphocyte epitope with strong immunogenicity in patients with hepatocellular carcinoma

α-Fetoprotein (AFP) is considered a good target for immunotherapy strategies against hepatocellular carcinoma (HCC); however, no immunodominant AFP-derived MHC class II-restricted helper T-lymphocyte (HTL) epitope has been reported. Therefore, we identified novel AFP-derived HTL epitopes possessing...

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Detalles Bibliográficos
Autores principales:	Tamai, Toshikatsu, Mizukoshi, Eishiro, Kumagai, Masashi, Terashima, Takeshi, Iida, Noriho, Kitahara, Masaaki, Shimakami, Tetsuro, Kitamura, Kazuya, Arai, Kuniaki, Yamashita, Taro, Sakai, Yoshio, Yamashita, Tatsuya, Honda, Masao, Fushimi, Kazumi, Kaneko, Shuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055302/ https://www.ncbi.nlm.nih.gov/pubmed/32132566 http://dx.doi.org/10.1038/s41598-020-60843-4

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