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Lactation stage impacts the glycolytic function of bovine CD4(+) T cells during ex vivo activation

Dairy cattle undergo dynamic physiological changes over the course of a full lactation into the dry period, which impacts their immunocompetence. During activation, T cells undergo a characteristic rewiring to increase the uptake of glucose and metabolically reprogram to favor aerobic glycolysis ove...

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Detalles Bibliográficos
Autores principales: Eder, Jordan M., Gorden, Patrick J., Lippolis, John D., Reinhardt, Timothy A., Sacco, Randy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055328/
https://www.ncbi.nlm.nih.gov/pubmed/32132555
http://dx.doi.org/10.1038/s41598-020-60691-2