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Acute effects of ambient PM(2.5) on lung function among schoolchildren

Previous studies have found that fine particulate matter (PM(2.5)) air pollution is associated with decreased lung function. However, most current research focuses on children with asthma, leading to small sample sizes and limited generalization of results. The current study aimed to measure the sho...

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Autores principales: Xu, Dandan, Chen, Yuan, Wu, Lizhi, He, Shengliang, Xu, Peiwei, Zhang, Yongli, Luo, Jinbin, Ye, Xialiang, Chen, Zhijian, Wang, Xiaofeng, Lou, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055357/
https://www.ncbi.nlm.nih.gov/pubmed/32132612
http://dx.doi.org/10.1038/s41598-020-61003-4
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author Xu, Dandan
Chen, Yuan
Wu, Lizhi
He, Shengliang
Xu, Peiwei
Zhang, Yongli
Luo, Jinbin
Ye, Xialiang
Chen, Zhijian
Wang, Xiaofeng
Lou, Xiaoming
author_facet Xu, Dandan
Chen, Yuan
Wu, Lizhi
He, Shengliang
Xu, Peiwei
Zhang, Yongli
Luo, Jinbin
Ye, Xialiang
Chen, Zhijian
Wang, Xiaofeng
Lou, Xiaoming
author_sort Xu, Dandan
collection PubMed
description Previous studies have found that fine particulate matter (PM(2.5)) air pollution is associated with decreased lung function. However, most current research focuses on children with asthma, leading to small sample sizes and limited generalization of results. The current study aimed to measure the short-term and lag effects of PM(2.5) among school-aged children using repeated measurements of lung function.This prospective panel study included 848 schoolchildren in Zhejiang Province, China. Each year from 2014–2017, two lung function tests were conducted from November 15(th) to December 31(st). Daily air pollution data were derived from the monitoring stations nearest to the schools. A mixed-effects regression model was used to investigate the relationship between PM(2.5) and lung function. The effect of PM(2.5) on lung function reached its greatest at 1-day moving average PM(2.5) exposure. For every 10 μg/m(3) increase in the 1-day moving average PM(2.5) concentration, Forced Vital Capacity (FVC) of children decreased by 33.74 mL (95% CI: 22.52, 44.96), 1-s Forced Expiratory Volume (FEV(1)) decreased by 32.56 mL (95% CI: 21.41, 43.70), and Peak Expiratory Flow (PEF) decreased by 67.45 mL/s (95% CI: 45.64, 89.25). Stronger associations were found in children living in homes with smokers. Short-term exposure to PM(2.5) was associated with reductions in schoolchildren’s lung function. This finding indicates that short-term exposure to PM(2.5) is harmful to children’s respiratory health, and appropriate protective measures should be taken to reduce the adverse effects of air pollution on children’s health.
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spelling pubmed-70553572020-03-12 Acute effects of ambient PM(2.5) on lung function among schoolchildren Xu, Dandan Chen, Yuan Wu, Lizhi He, Shengliang Xu, Peiwei Zhang, Yongli Luo, Jinbin Ye, Xialiang Chen, Zhijian Wang, Xiaofeng Lou, Xiaoming Sci Rep Article Previous studies have found that fine particulate matter (PM(2.5)) air pollution is associated with decreased lung function. However, most current research focuses on children with asthma, leading to small sample sizes and limited generalization of results. The current study aimed to measure the short-term and lag effects of PM(2.5) among school-aged children using repeated measurements of lung function.This prospective panel study included 848 schoolchildren in Zhejiang Province, China. Each year from 2014–2017, two lung function tests were conducted from November 15(th) to December 31(st). Daily air pollution data were derived from the monitoring stations nearest to the schools. A mixed-effects regression model was used to investigate the relationship between PM(2.5) and lung function. The effect of PM(2.5) on lung function reached its greatest at 1-day moving average PM(2.5) exposure. For every 10 μg/m(3) increase in the 1-day moving average PM(2.5) concentration, Forced Vital Capacity (FVC) of children decreased by 33.74 mL (95% CI: 22.52, 44.96), 1-s Forced Expiratory Volume (FEV(1)) decreased by 32.56 mL (95% CI: 21.41, 43.70), and Peak Expiratory Flow (PEF) decreased by 67.45 mL/s (95% CI: 45.64, 89.25). Stronger associations were found in children living in homes with smokers. Short-term exposure to PM(2.5) was associated with reductions in schoolchildren’s lung function. This finding indicates that short-term exposure to PM(2.5) is harmful to children’s respiratory health, and appropriate protective measures should be taken to reduce the adverse effects of air pollution on children’s health. Nature Publishing Group UK 2020-03-04 /pmc/articles/PMC7055357/ /pubmed/32132612 http://dx.doi.org/10.1038/s41598-020-61003-4 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Xu, Dandan
Chen, Yuan
Wu, Lizhi
He, Shengliang
Xu, Peiwei
Zhang, Yongli
Luo, Jinbin
Ye, Xialiang
Chen, Zhijian
Wang, Xiaofeng
Lou, Xiaoming
Acute effects of ambient PM(2.5) on lung function among schoolchildren
title Acute effects of ambient PM(2.5) on lung function among schoolchildren
title_full Acute effects of ambient PM(2.5) on lung function among schoolchildren
title_fullStr Acute effects of ambient PM(2.5) on lung function among schoolchildren
title_full_unstemmed Acute effects of ambient PM(2.5) on lung function among schoolchildren
title_short Acute effects of ambient PM(2.5) on lung function among schoolchildren
title_sort acute effects of ambient pm(2.5) on lung function among schoolchildren
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055357/
https://www.ncbi.nlm.nih.gov/pubmed/32132612
http://dx.doi.org/10.1038/s41598-020-61003-4
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