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The structural study of mutation-induced inactivation of human muscarinic receptor M4

Human muscarinic receptor M4 belongs to the class A subfamily of the G-protein-coupled receptors (GPCRs). M4 has emerged as an attractive drug target for the treatment of Alzheimer’s disease and schizophrenia. Recent results showed that M4-mediated cholinergic transmission is related to motor sympto...

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Detalles Bibliográficos
Autores principales:	Wang, Jingjing, Wu, Meng, Wu, Lijie, Xu, Yueming, Li, Fei, Wu, Yiran, Popov, Petr, Wang, Lin, Bai, Fang, Zhao, Suwen, Liu, Zhi-Jie, Hua, Tian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2020
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055379/ https://www.ncbi.nlm.nih.gov/pubmed/32148857 http://dx.doi.org/10.1107/S2052252520000597

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