Isomorphism: ‘molecular similarity to crystal structure similarity’ in multicomponent forms of analgesic drugs tolfenamic and mefenamic acid

The non-steroidal anti-inflammatory drugs mefenamic acid (MFA) and tolfenamic acid (TFA) have a close resemblance in their molecular scaffold, whereby a methyl group in MFA is substituted by a chloro group in TFA. The present study demonstrates the isomorphous nature of these compounds in a series o...

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Detalles Bibliográficos
Autores principales: Ranjan, Subham, Devarapalli, Ramesh, Kundu, Sudeshna, Saha, Subhankar, Deolka, Shubham, Vangala, Venu R., Reddy, C. Malla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055380/
https://www.ncbi.nlm.nih.gov/pubmed/32148846
http://dx.doi.org/10.1107/S205225251901604X

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055380/
https://www.ncbi.nlm.nih.gov/pubmed/32148846
http://dx.doi.org/10.1107/S205225251901604X

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