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Synthetic ablations in the C. elegans nervous system

Synthetic lethality, the finding that the simultaneous knockout of two or more individually nonessential genes leads to cell or organism death, has offered a systematic framework to explore cellular function, and also offered therapeutic applications. Yet the concept lacks its parallel in neuroscien...

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Detalles Bibliográficos
Autores principales: Towlson, Emma K., Barabási, Albert-László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MIT Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055645/
https://www.ncbi.nlm.nih.gov/pubmed/32166208
http://dx.doi.org/10.1162/netn_a_00115