Inhibition of the oligosaccharyl transferase in Caenorhabditis elegans that compromises ER proteostasis suppresses p38-dependent protection against pathogenic bacteria

The oligosaccharyl transferase (OST) protein complex mediates the N-linked glycosylation of substrate proteins in the endoplasmic reticulum (ER), which regulates stability, activity, and localization of its substrates. Although many OST substrate proteins have been identified, the physiological role...

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Detalles Bibliográficos
Autores principales: Jeong, Dae-Eun, Lee, Yujin, Ham, Seokjin, Lee, Dongyeop, Kwon, Sujeong, Park, Hae-Eun H., Hwang, Sun-Young, Yoo, Joo-Yeon, Roh, Tae-Young, Lee, Seung-Jae V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055741/
https://www.ncbi.nlm.nih.gov/pubmed/32130226
http://dx.doi.org/10.1371/journal.pgen.1008617

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