Cell-free chromatin particles released from dying host cells are global instigators of endotoxin sepsis in mice

We have earlier reported that cell-free chromatin (cfCh) particles that are released from dying cells, or those that circulate blood, can readily enter into healthy cells, illegitimately integrate into their genomes and induce dsDNA breaks, apoptosis and intense activation of inflammatory cytokines....

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Detalles Bibliográficos
Autores principales: Mittra, Indraneel, Pal, Kavita, Pancholi, Namrata, Tidke, Pritishkumar, Siddiqui, Sophiya, Rane, Bhagyeshri, D’souza, Jenevieve, Shaikh, Alfina, Parab, Saili, Shinde, Sushma, Jadhav, Vishal, Shende, Soniya, Raghuram, Gorantla V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055819/
https://www.ncbi.nlm.nih.gov/pubmed/32130239
http://dx.doi.org/10.1371/journal.pone.0229017

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