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Influence of EGFR-activating mutations on sensitivity to tyrosine kinase inhibitors in a KRAS mutant non-small cell lung cancer cell line

In non-small cell lung cancer (NSCLC), oncogenic driver mutations including those in KRAS and EGFR are typically mutually exclusive. However, recent reports indicate that multiple driver mutations are found in a certain percentage of cancers, and that the therapeutic responses of such cases with co-...

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Detalles Bibliográficos
Autores principales:	Tsukumo, Yoshinori, Naito, Mikihiko, Suzuki, Takayoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055889/ https://www.ncbi.nlm.nih.gov/pubmed/32130260 http://dx.doi.org/10.1371/journal.pone.0229712

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