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Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes
Base J, β-D-glucosyl-hydroxymethyluracil, is a modification of thymine DNA base involved in RNA Polymerase (Pol) II transcription termination in kinetoplastid protozoa. Little is understood regarding how specific thymine residues are targeted for J-modification or the mechanism of J regulated transc...
Autores principales: | Kieft, Rudo, Zhang, Yang, Marand, Alexandre P., Moran, Jose Dagoberto, Bridger, Robert, Wells, Lance, Schmitz, Robert J., Sabatini, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055916/ https://www.ncbi.nlm.nih.gov/pubmed/32084124 http://dx.doi.org/10.1371/journal.pgen.1008390 |
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