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Disruption of Pressure-Induced Ca(2+) Spark Vasoregulation of Resistance Arteries, Rather Than Endothelial Dysfunction, Underlies Obesity-Related Hypertension
Obesity-related hypertension is one of the world’s leading causes of death and yet little is understood as to how it develops. As a result, effective targeted therapies are lacking and pharmacological treatment is unfocused. To investigate underlying microvascular mechanisms, we studied small artery...
Autores principales: | Greenstein, Adam S., Kadir, Sharifah Zamiah Abdul Syed, Csato, Viktoria, Sugden, Sarah A., Baylie, Rachael A., Eisner, David A., Nelson, Mark T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott, Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055934/ https://www.ncbi.nlm.nih.gov/pubmed/31865779 http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13540 |
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