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Cardiovascular Effects of Pharmacological Targeting of Sphingosine Kinase 1

High blood pressure is a risk factor for cardiovascular diseases. Ang II (angiotensin II), a key pro-hypertensive hormone, mediates target organ consequences such as endothelial dysfunction and cardiac hypertrophy. S1P (sphingosine-1-phosphate), produced by Sphk1 (sphingosine kinase 1), plays a pivo...

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Detalles Bibliográficos
Autores principales:	Józefczuk, Ewelina, Nosalski, Ryszard, Saju, Blessy, Crespo, Eva, Szczepaniak, Piotr, Guzik, Tomasz Jan, Siedlinski, Mateusz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott, Williams & Wilkins 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055939/ https://www.ncbi.nlm.nih.gov/pubmed/31838904 http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13450

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