Inflammasome activation and IL-1 signaling during placental malaria induce poor pregnancy outcomes

Placental malaria (PM) is associated with severe inflammation leading to abortion, preterm delivery, and intrauterine growth restriction. Innate immunity responses play critical roles, but the mechanisms underlying placental immunopathology are still unclear. Here, we investigated the role of inflam...

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Detalles Bibliográficos
Autores principales: Reis, Aramys S., Barboza, Renato, Murillo, Oscar, Barateiro, André, Peixoto, Erika P. M., Lima, Flávia A., Gomes, Vinícius M., Dombrowski, Jamille G., Leal, Vinícius N. C., Araujo, Franciele, Bandeira, Carla L., Araujo, Rosana B. D., Neres, Rita, Souza, Rodrigo M., Costa, Fabio T. M., Pontillo, Alessandra, Bevilacqua, Estela, Wrenger, Carsten, Wunderlich, Gerhard, Palmisano, Giuseppe, Labriola, Leticia, Bortoluci, Karina R., Penha-Gonçalves, Carlos, Gonçalves, Lígia A., Epiphanio, Sabrina, Marinho, Claudio R. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056302/
https://www.ncbi.nlm.nih.gov/pubmed/32181339
http://dx.doi.org/10.1126/sciadv.aax6346

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