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Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis and cytopenias due to uncontrolled programmed cell death. The presence of pro-inflammatory cytokines and constitutive activation of innate immunity signals in MDS cells suggest inflammatory cell death, such as necroptosis...

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Detalles Bibliográficos
Autores principales:	Montalban-Bravo, Guillermo, Class, Caleb A., Ganan-Gomez, Irene, Kanagal-Shamanna, Rashmi, Sasaki, Koji, Richard-Carpentier, Guillaume, Naqvi, Kiran, Wei, Yue, Yang, Hui, Soltysiak, Kelly A., Chien, Kelly, Bueso-Ramos, Carlos, Do, Kim-Anh, Kantarjian, Hagop, Garcia-Manero, Guillermo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056563/ https://www.ncbi.nlm.nih.gov/pubmed/31719677 http://dx.doi.org/10.1038/s41375-019-0623-5

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