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Development and Preclinical Evaluation of an Integrase Defective Lentiviral Vector Vaccine Expressing the HIVACAT T Cell Immunogen in Mice

Cellular immune responses play a fundamental role in controlling viral replication and AIDS progression in human immunodeficiency virus (HIV)-infected subjects and in simian immunodeficiency virus (SIV)-infected macaques. Integrase defective lentiviral vector (IDLV) represents a promising vaccine ca...

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Detalles Bibliográficos
Autores principales: Gallinaro, Alessandra, Borghi, Martina, Pirillo, Maria Franca, Cecchetti, Serena, Bona, Roberta, Canitano, Andrea, Michelini, Zuleika, Di Virgilio, Antonio, Olvera, Alex, Brander, Christian, Negri, Donatella, Cara, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056611/
https://www.ncbi.nlm.nih.gov/pubmed/32154327
http://dx.doi.org/10.1016/j.omtm.2020.01.013