Cargando…
Development and Preclinical Evaluation of an Integrase Defective Lentiviral Vector Vaccine Expressing the HIVACAT T Cell Immunogen in Mice
Cellular immune responses play a fundamental role in controlling viral replication and AIDS progression in human immunodeficiency virus (HIV)-infected subjects and in simian immunodeficiency virus (SIV)-infected macaques. Integrase defective lentiviral vector (IDLV) represents a promising vaccine ca...
Autores principales: | Gallinaro, Alessandra, Borghi, Martina, Pirillo, Maria Franca, Cecchetti, Serena, Bona, Roberta, Canitano, Andrea, Michelini, Zuleika, Di Virgilio, Antonio, Olvera, Alex, Brander, Christian, Negri, Donatella, Cara, Andrea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056611/ https://www.ncbi.nlm.nih.gov/pubmed/32154327 http://dx.doi.org/10.1016/j.omtm.2020.01.013 |
Ejemplares similares
-
Integrase-Defective Lentiviral Vector Is an Efficient Vaccine Platform for Cancer Immunotherapy
por: Morante, Valeria, et al.
Publicado: (2021) -
Safety and efficiency modifications of SIV-based integrase-defective lentiviral vectors for immunization
por: Bona, Roberta, et al.
Publicado: (2021) -
Persistent immunogenicity of integrase defective lentiviral vectors delivering membrane-tethered native-like HIV-1 envelope trimers
por: Gallinaro, Alessandra, et al.
Publicado: (2022) -
Integrase Defective Lentiviral Vector as a Vaccine Platform for Delivering Influenza Antigens
por: Gallinaro, Alessandra, et al.
Publicado: (2018) -
Different configurations of SARS-CoV-2 spike protein delivered by integrase-defective lentiviral vectors induce persistent functional immune responses, characterized by distinct immunogenicity profiles
por: Borghi, Martina, et al.
Publicado: (2023)