Cargando…
Comparing the genetic architecture of childhood behavioral problems across socioeconomic strata in the Netherlands and the United Kingdom
Socioeconomic status (SES) affects the development of childhood behavioral problems. It has been frequently observed that children from low SES background tend to show more behavioral problems. There also is some evidence that SES has a moderating effect on the causes of individual differences in ch...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056693/ https://www.ncbi.nlm.nih.gov/pubmed/31154517 http://dx.doi.org/10.1007/s00787-019-01357-x |
_version_ | 1783503519187206144 |
---|---|
author | Hendriks, A. M. Finkenauer, C. Nivard, M. G. Van Beijsterveldt, C. E. M. Plomin, R. J. Boomsma, D. I. Bartels, M. |
author_facet | Hendriks, A. M. Finkenauer, C. Nivard, M. G. Van Beijsterveldt, C. E. M. Plomin, R. J. Boomsma, D. I. Bartels, M. |
author_sort | Hendriks, A. M. |
collection | PubMed |
description | Socioeconomic status (SES) affects the development of childhood behavioral problems. It has been frequently observed that children from low SES background tend to show more behavioral problems. There also is some evidence that SES has a moderating effect on the causes of individual differences in childhood behavioral problems, with lower heritability estimates and a stronger contribution of environmental factors in low SES groups. The aim of the present study was to examine whether the genetic architecture of childhood behavioral problems suggests the presence of protective and/or harmful effects across socioeconomic strata, in two countries with different levels of socioeconomic disparity: the Netherlands and the United Kingdom. We analyzed data from 7-year-old twins from the Netherlands Twin Register (N = 24,112 twins) and the Twins Early Development Study (N = 19,644 twins). The results revealed a nonlinear moderation effect of SES on the contribution of genetic and environmental factors to individual differences in childhood behavioral problems. The heritability was higher, the contribution of the shared environment was lower, and the contribution of the nonshared environment was higher, for children from high SES families, compared to children from low or medium SES families. The pattern was similar for Dutch and UK families. We discuss the importance of these findings for prevention and intervention goals. |
format | Online Article Text |
id | pubmed-7056693 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-70566932020-03-16 Comparing the genetic architecture of childhood behavioral problems across socioeconomic strata in the Netherlands and the United Kingdom Hendriks, A. M. Finkenauer, C. Nivard, M. G. Van Beijsterveldt, C. E. M. Plomin, R. J. Boomsma, D. I. Bartels, M. Eur Child Adolesc Psychiatry Original Contribution Socioeconomic status (SES) affects the development of childhood behavioral problems. It has been frequently observed that children from low SES background tend to show more behavioral problems. There also is some evidence that SES has a moderating effect on the causes of individual differences in childhood behavioral problems, with lower heritability estimates and a stronger contribution of environmental factors in low SES groups. The aim of the present study was to examine whether the genetic architecture of childhood behavioral problems suggests the presence of protective and/or harmful effects across socioeconomic strata, in two countries with different levels of socioeconomic disparity: the Netherlands and the United Kingdom. We analyzed data from 7-year-old twins from the Netherlands Twin Register (N = 24,112 twins) and the Twins Early Development Study (N = 19,644 twins). The results revealed a nonlinear moderation effect of SES on the contribution of genetic and environmental factors to individual differences in childhood behavioral problems. The heritability was higher, the contribution of the shared environment was lower, and the contribution of the nonshared environment was higher, for children from high SES families, compared to children from low or medium SES families. The pattern was similar for Dutch and UK families. We discuss the importance of these findings for prevention and intervention goals. Springer Berlin Heidelberg 2019-06-01 2020 /pmc/articles/PMC7056693/ /pubmed/31154517 http://dx.doi.org/10.1007/s00787-019-01357-x Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Contribution Hendriks, A. M. Finkenauer, C. Nivard, M. G. Van Beijsterveldt, C. E. M. Plomin, R. J. Boomsma, D. I. Bartels, M. Comparing the genetic architecture of childhood behavioral problems across socioeconomic strata in the Netherlands and the United Kingdom |
title | Comparing the genetic architecture of childhood behavioral problems across socioeconomic strata in the Netherlands and the United Kingdom |
title_full | Comparing the genetic architecture of childhood behavioral problems across socioeconomic strata in the Netherlands and the United Kingdom |
title_fullStr | Comparing the genetic architecture of childhood behavioral problems across socioeconomic strata in the Netherlands and the United Kingdom |
title_full_unstemmed | Comparing the genetic architecture of childhood behavioral problems across socioeconomic strata in the Netherlands and the United Kingdom |
title_short | Comparing the genetic architecture of childhood behavioral problems across socioeconomic strata in the Netherlands and the United Kingdom |
title_sort | comparing the genetic architecture of childhood behavioral problems across socioeconomic strata in the netherlands and the united kingdom |
topic | Original Contribution |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056693/ https://www.ncbi.nlm.nih.gov/pubmed/31154517 http://dx.doi.org/10.1007/s00787-019-01357-x |
work_keys_str_mv | AT hendriksam comparingthegeneticarchitectureofchildhoodbehavioralproblemsacrosssocioeconomicstratainthenetherlandsandtheunitedkingdom AT finkenauerc comparingthegeneticarchitectureofchildhoodbehavioralproblemsacrosssocioeconomicstratainthenetherlandsandtheunitedkingdom AT nivardmg comparingthegeneticarchitectureofchildhoodbehavioralproblemsacrosssocioeconomicstratainthenetherlandsandtheunitedkingdom AT vanbeijsterveldtcem comparingthegeneticarchitectureofchildhoodbehavioralproblemsacrosssocioeconomicstratainthenetherlandsandtheunitedkingdom AT plominrj comparingthegeneticarchitectureofchildhoodbehavioralproblemsacrosssocioeconomicstratainthenetherlandsandtheunitedkingdom AT boomsmadi comparingthegeneticarchitectureofchildhoodbehavioralproblemsacrosssocioeconomicstratainthenetherlandsandtheunitedkingdom AT bartelsm comparingthegeneticarchitectureofchildhoodbehavioralproblemsacrosssocioeconomicstratainthenetherlandsandtheunitedkingdom |