Cargando…
FAIM Is a Non-redundant Defender of Cellular Viability in the Face of Heat and Oxidative Stress and Interferes With Accumulation of Stress-Induced Protein Aggregates
A key element of cellular homeostasis lies in the way in which misfolded and dysfunctional proteins are handled. Cellular pathways that include proteasomal destruction and autophagic disposal are components of normal proteostasis. Here we report a novel molecule that plays a non-redundant role in ma...
Autores principales: | Kaku, Hiroaki, Rothstein, Thomas L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056718/ https://www.ncbi.nlm.nih.gov/pubmed/32175331 http://dx.doi.org/10.3389/fmolb.2020.00032 |
Ejemplares similares
-
Small Heat Shock Proteins Collaborate with FAIM to Prevent Accumulation of Misfolded Protein Aggregates
por: Kaku, Hiroaki, et al.
Publicado: (2022) -
FAIM Opposes Aggregation of Mutant SOD1 That Typifies Some Forms of Familial Amyotrophic Lateral Sclerosis
por: Kaku, Hiroaki, et al.
Publicado: (2020) -
Drug Resistance in Glioblastoma: The Two Faces of Oxidative Stress
por: Olivier, Christophe, et al.
Publicado: (2021) -
SGnn: A Web Server for the Prediction of Prion-Like Domains Recruitment to Stress Granules Upon Heat Stress
por: Iglesias, Valentín, et al.
Publicado: (2021) -
Resisting the Heat: Bacterial Disaggregases Rescue Cells From Devastating Protein Aggregation
por: Katikaridis, Panagiotis, et al.
Publicado: (2021)