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Enhanced Phenotype Definition for Precision Isolation of Precursor Exhausted Tumor-Infiltrating CD8 T Cells

In the context of adoptive T cell transfer (ACT) for cancer treatment, it is crucial to generate in vitro large amounts of tumor-specific CD8 T cells with high potential to persist in vivo. PD-1, Tim3, and CD39 have been proposed as markers of tumor-specific tumor-infiltrating CD8 T lymphocytes (CD8...

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Detalles Bibliográficos
Autores principales:	Martinez-Usatorre, Amaia, Carmona, Santiago J., Godfroid, Céline, Yacoub Maroun, Céline, Labiano, Sara, Romero, Pedro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056729/ https://www.ncbi.nlm.nih.gov/pubmed/32174925 http://dx.doi.org/10.3389/fimmu.2020.00340

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