Blockade of Stromal Gas6 Alters Cancer Cell Plasticity, Activates NK Cells, and Inhibits Pancreatic Cancer Metastasis

Pancreatic ductal adenocarcinoma (PDA) is one of the deadliest cancers due to its aggressive and metastatic nature. PDA is characterized by a rich tumor stroma with abundant macrophages, fibroblasts, and collagen deposition that can represent up to 90% of the tumor mass. Activation of the tyrosine k...

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Detalles Bibliográficos
Autores principales: Ireland, Lucy, Luckett, Teifion, Schmid, Michael C., Mielgo, Ainhoa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056881/
https://www.ncbi.nlm.nih.gov/pubmed/32174917
http://dx.doi.org/10.3389/fimmu.2020.00297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056881/
https://www.ncbi.nlm.nih.gov/pubmed/32174917
http://dx.doi.org/10.3389/fimmu.2020.00297

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