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Systems Genetics of Optic Nerve Axon Necrosis During Glaucoma
In this study, we identify genomic regions that modulate the number of necrotic axons in optic nerves of a family of mice, some of which have severe glaucoma, and define a set of high priority positional candidate genes that modulate retinal ganglion cell (RGC) axonal degeneration. A large cohort of...
Autores principales: | Stiemke, Andrew B., Sah, Eric, Simpson, Raven N., Lu, Lu, Williams, Robert W., Jablonski, Monica M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056908/ https://www.ncbi.nlm.nih.gov/pubmed/32174956 http://dx.doi.org/10.3389/fgene.2020.00031 |
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