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shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes

Non-circular plots of whole genomes are natural representations of genomic data aligned along all chromosomes. Currently, there is no specialized graphical user interface (GUI) designed to produce non-circular whole genome diagrams, and the use of existing tools requires considerable coding effort f...

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Detalles Bibliográficos
Autores principales: Yu, Yiming, Yao, Wen, Wang, Yuping, Huang, Fangfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056921/
https://www.ncbi.nlm.nih.gov/pubmed/31931182
http://dx.doi.org/10.1016/j.gpb.2019.07.003
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author Yu, Yiming
Yao, Wen
Wang, Yuping
Huang, Fangfang
author_facet Yu, Yiming
Yao, Wen
Wang, Yuping
Huang, Fangfang
author_sort Yu, Yiming
collection PubMed
description Non-circular plots of whole genomes are natural representations of genomic data aligned along all chromosomes. Currently, there is no specialized graphical user interface (GUI) designed to produce non-circular whole genome diagrams, and the use of existing tools requires considerable coding effort from users. Moreover, such tools also require improvement, including the addition of new functionalities. To address these issues, we developed a new R/Shiny application, named shinyChromosome, as a GUI for the interactive creation of non-circular whole genome diagrams. shinyChromosome can be easily installed on personal computers for own use as well as on local or public servers for community use. Publication-quality images can be readily generated and annotated from user input using diverse widgets. shinyChromosome is deployed at http://150.109.59.144:3838/shinyChromosome/, http://shinyChromosome.ncpgr.cn, and https://yimingyu.shinyapps.io/shinyChromosome for online use. The source code and manual of shinyChromosome are freely available at https://github.com/venyao/shinyChromosome.
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spelling pubmed-70569212020-03-09 shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes Yu, Yiming Yao, Wen Wang, Yuping Huang, Fangfang Genomics Proteomics Bioinformatics Application Note Non-circular plots of whole genomes are natural representations of genomic data aligned along all chromosomes. Currently, there is no specialized graphical user interface (GUI) designed to produce non-circular whole genome diagrams, and the use of existing tools requires considerable coding effort from users. Moreover, such tools also require improvement, including the addition of new functionalities. To address these issues, we developed a new R/Shiny application, named shinyChromosome, as a GUI for the interactive creation of non-circular whole genome diagrams. shinyChromosome can be easily installed on personal computers for own use as well as on local or public servers for community use. Publication-quality images can be readily generated and annotated from user input using diverse widgets. shinyChromosome is deployed at http://150.109.59.144:3838/shinyChromosome/, http://shinyChromosome.ncpgr.cn, and https://yimingyu.shinyapps.io/shinyChromosome for online use. The source code and manual of shinyChromosome are freely available at https://github.com/venyao/shinyChromosome. Elsevier 2019-10 2020-01-11 /pmc/articles/PMC7056921/ /pubmed/31931182 http://dx.doi.org/10.1016/j.gpb.2019.07.003 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Application Note
Yu, Yiming
Yao, Wen
Wang, Yuping
Huang, Fangfang
shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes
title shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes
title_full shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes
title_fullStr shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes
title_full_unstemmed shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes
title_short shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes
title_sort shinychromosome: an r/shiny application for interactive creation of non-circular plots of whole genomes
topic Application Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056921/
https://www.ncbi.nlm.nih.gov/pubmed/31931182
http://dx.doi.org/10.1016/j.gpb.2019.07.003
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