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shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes
Non-circular plots of whole genomes are natural representations of genomic data aligned along all chromosomes. Currently, there is no specialized graphical user interface (GUI) designed to produce non-circular whole genome diagrams, and the use of existing tools requires considerable coding effort f...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056921/ https://www.ncbi.nlm.nih.gov/pubmed/31931182 http://dx.doi.org/10.1016/j.gpb.2019.07.003 |
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author | Yu, Yiming Yao, Wen Wang, Yuping Huang, Fangfang |
author_facet | Yu, Yiming Yao, Wen Wang, Yuping Huang, Fangfang |
author_sort | Yu, Yiming |
collection | PubMed |
description | Non-circular plots of whole genomes are natural representations of genomic data aligned along all chromosomes. Currently, there is no specialized graphical user interface (GUI) designed to produce non-circular whole genome diagrams, and the use of existing tools requires considerable coding effort from users. Moreover, such tools also require improvement, including the addition of new functionalities. To address these issues, we developed a new R/Shiny application, named shinyChromosome, as a GUI for the interactive creation of non-circular whole genome diagrams. shinyChromosome can be easily installed on personal computers for own use as well as on local or public servers for community use. Publication-quality images can be readily generated and annotated from user input using diverse widgets. shinyChromosome is deployed at http://150.109.59.144:3838/shinyChromosome/, http://shinyChromosome.ncpgr.cn, and https://yimingyu.shinyapps.io/shinyChromosome for online use. The source code and manual of shinyChromosome are freely available at https://github.com/venyao/shinyChromosome. |
format | Online Article Text |
id | pubmed-7056921 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-70569212020-03-09 shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes Yu, Yiming Yao, Wen Wang, Yuping Huang, Fangfang Genomics Proteomics Bioinformatics Application Note Non-circular plots of whole genomes are natural representations of genomic data aligned along all chromosomes. Currently, there is no specialized graphical user interface (GUI) designed to produce non-circular whole genome diagrams, and the use of existing tools requires considerable coding effort from users. Moreover, such tools also require improvement, including the addition of new functionalities. To address these issues, we developed a new R/Shiny application, named shinyChromosome, as a GUI for the interactive creation of non-circular whole genome diagrams. shinyChromosome can be easily installed on personal computers for own use as well as on local or public servers for community use. Publication-quality images can be readily generated and annotated from user input using diverse widgets. shinyChromosome is deployed at http://150.109.59.144:3838/shinyChromosome/, http://shinyChromosome.ncpgr.cn, and https://yimingyu.shinyapps.io/shinyChromosome for online use. The source code and manual of shinyChromosome are freely available at https://github.com/venyao/shinyChromosome. Elsevier 2019-10 2020-01-11 /pmc/articles/PMC7056921/ /pubmed/31931182 http://dx.doi.org/10.1016/j.gpb.2019.07.003 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Application Note Yu, Yiming Yao, Wen Wang, Yuping Huang, Fangfang shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes |
title | shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes |
title_full | shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes |
title_fullStr | shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes |
title_full_unstemmed | shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes |
title_short | shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes |
title_sort | shinychromosome: an r/shiny application for interactive creation of non-circular plots of whole genomes |
topic | Application Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056921/ https://www.ncbi.nlm.nih.gov/pubmed/31931182 http://dx.doi.org/10.1016/j.gpb.2019.07.003 |
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