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Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study
BACKGROUND: Primary hyperparathyroidism (PHPT) and thyroid diseases are a frequent concomitant occurrence, but the surgical approach to associated disease is still debated. METHODS: We retrospectively evaluated a series of PHPT patients focusing on thyroid disease and surgery. RESULTS: Among 238 PHP...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057020/ https://www.ncbi.nlm.nih.gov/pubmed/32148486 http://dx.doi.org/10.1155/2020/2182539 |
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author | Castellano, Elena Benso, Paolo Attanasio, Roberto Boriano, Alberto Lauro, Corrado Borretta, Giorgio Borghi, Felice |
author_facet | Castellano, Elena Benso, Paolo Attanasio, Roberto Boriano, Alberto Lauro, Corrado Borretta, Giorgio Borghi, Felice |
author_sort | Castellano, Elena |
collection | PubMed |
description | BACKGROUND: Primary hyperparathyroidism (PHPT) and thyroid diseases are a frequent concomitant occurrence, but the surgical approach to associated disease is still debated. METHODS: We retrospectively evaluated a series of PHPT patients focusing on thyroid disease and surgery. RESULTS: Among 238 PHPT patients undergoing parathyroidectomy (PTX) between 2002 and 2017, 128 were affected also by a benign thyroid disease, namely, goiter in 118 (76 multinodular (MNG) and 42 uninodular (UNG)), autoimmune thyroiditis in 10, and hyperthyroidism in 21. Surgical approach was unilateral neck exploration (UNE) in 59 patients and bilateral neck exploration (BNE) in 69. The PHPT cure rate was 94%. On comparing patients submitted to PTX only and PTX plus thyroidectomy (TX), in the latter MNG and hyperthyroidism were more frequent, and surgical time and length of stay were longer. No difference in surgical complications was found between patients undergoing UNE and BNE. CONCLUSION: PHPT patients with a concomitant thyroid disease underwent double surgery in almost two-thirds of the cases, mostly by BNE. The main factors driving the decision to perform concomitant PTX and TX were the presence of thyroid nodular disease with the nodule site ipsilateral to the presurgically localized parathyroid adenoma. |
format | Online Article Text |
id | pubmed-7057020 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-70570202020-03-08 Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study Castellano, Elena Benso, Paolo Attanasio, Roberto Boriano, Alberto Lauro, Corrado Borretta, Giorgio Borghi, Felice Int J Endocrinol Research Article BACKGROUND: Primary hyperparathyroidism (PHPT) and thyroid diseases are a frequent concomitant occurrence, but the surgical approach to associated disease is still debated. METHODS: We retrospectively evaluated a series of PHPT patients focusing on thyroid disease and surgery. RESULTS: Among 238 PHPT patients undergoing parathyroidectomy (PTX) between 2002 and 2017, 128 were affected also by a benign thyroid disease, namely, goiter in 118 (76 multinodular (MNG) and 42 uninodular (UNG)), autoimmune thyroiditis in 10, and hyperthyroidism in 21. Surgical approach was unilateral neck exploration (UNE) in 59 patients and bilateral neck exploration (BNE) in 69. The PHPT cure rate was 94%. On comparing patients submitted to PTX only and PTX plus thyroidectomy (TX), in the latter MNG and hyperthyroidism were more frequent, and surgical time and length of stay were longer. No difference in surgical complications was found between patients undergoing UNE and BNE. CONCLUSION: PHPT patients with a concomitant thyroid disease underwent double surgery in almost two-thirds of the cases, mostly by BNE. The main factors driving the decision to perform concomitant PTX and TX were the presence of thyroid nodular disease with the nodule site ipsilateral to the presurgically localized parathyroid adenoma. Hindawi 2020-02-22 /pmc/articles/PMC7057020/ /pubmed/32148486 http://dx.doi.org/10.1155/2020/2182539 Text en Copyright © 2020 Elena Castellano et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Castellano, Elena Benso, Paolo Attanasio, Roberto Boriano, Alberto Lauro, Corrado Borretta, Giorgio Borghi, Felice Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study |
title | Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study |
title_full | Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study |
title_fullStr | Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study |
title_full_unstemmed | Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study |
title_short | Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study |
title_sort | surgical approach to primary hyperparathyroidism in patients with concomitant thyroid diseases: a retrospective single center study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057020/ https://www.ncbi.nlm.nih.gov/pubmed/32148486 http://dx.doi.org/10.1155/2020/2182539 |
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