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Early Recognition and Treatment of Malignant Hyperthermia in Pediatric Patient during Bronchoscopy
Malignant hyperthermia is a rare pharmacogenetic disorder triggered by depolarizing muscle relaxant and potent volatile anesthetic agents. An MH crisis is an emergency and life-threatening event requiring early recognition and prompt management. Dantrolene is the specific antagonist of MH. The autho...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057021/ https://www.ncbi.nlm.nih.gov/pubmed/32148968 http://dx.doi.org/10.1155/2020/6562896 |
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author | Lapisatepun, Warangkana Arkarattanakul, Supawan |
author_facet | Lapisatepun, Warangkana Arkarattanakul, Supawan |
author_sort | Lapisatepun, Warangkana |
collection | PubMed |
description | Malignant hyperthermia is a rare pharmacogenetic disorder triggered by depolarizing muscle relaxant and potent volatile anesthetic agents. An MH crisis is an emergency and life-threatening event requiring early recognition and prompt management. Dantrolene is the specific antagonist of MH. The authors report the case of a 9-year-old boy who underwent an emergency bronchoscopy to remove a foreign body and developed masseter rigidity after succinylcholine and sevoflurane exposure. The anesthesia team diagnosed an MH event, and the event was managed immediately with supportive treatment, dantrolene, being administered within 10 minutes. The patient survived and had a good outcome without any complications. We suggest that it is essential for anesthesia providers to recognize the need for intraoperative vigilance, prompt recognition, and treatment, and dantrolene sodium should be readily available in every hospital. |
format | Online Article Text |
id | pubmed-7057021 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-70570212020-03-06 Early Recognition and Treatment of Malignant Hyperthermia in Pediatric Patient during Bronchoscopy Lapisatepun, Warangkana Arkarattanakul, Supawan Case Rep Anesthesiol Case Report Malignant hyperthermia is a rare pharmacogenetic disorder triggered by depolarizing muscle relaxant and potent volatile anesthetic agents. An MH crisis is an emergency and life-threatening event requiring early recognition and prompt management. Dantrolene is the specific antagonist of MH. The authors report the case of a 9-year-old boy who underwent an emergency bronchoscopy to remove a foreign body and developed masseter rigidity after succinylcholine and sevoflurane exposure. The anesthesia team diagnosed an MH event, and the event was managed immediately with supportive treatment, dantrolene, being administered within 10 minutes. The patient survived and had a good outcome without any complications. We suggest that it is essential for anesthesia providers to recognize the need for intraoperative vigilance, prompt recognition, and treatment, and dantrolene sodium should be readily available in every hospital. Hindawi 2020-02-22 /pmc/articles/PMC7057021/ /pubmed/32148968 http://dx.doi.org/10.1155/2020/6562896 Text en Copyright © 2020 Warangkana Lapisatepun and Supawan Arkarattanakul. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Lapisatepun, Warangkana Arkarattanakul, Supawan Early Recognition and Treatment of Malignant Hyperthermia in Pediatric Patient during Bronchoscopy |
title | Early Recognition and Treatment of Malignant Hyperthermia in Pediatric Patient during Bronchoscopy |
title_full | Early Recognition and Treatment of Malignant Hyperthermia in Pediatric Patient during Bronchoscopy |
title_fullStr | Early Recognition and Treatment of Malignant Hyperthermia in Pediatric Patient during Bronchoscopy |
title_full_unstemmed | Early Recognition and Treatment of Malignant Hyperthermia in Pediatric Patient during Bronchoscopy |
title_short | Early Recognition and Treatment of Malignant Hyperthermia in Pediatric Patient during Bronchoscopy |
title_sort | early recognition and treatment of malignant hyperthermia in pediatric patient during bronchoscopy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057021/ https://www.ncbi.nlm.nih.gov/pubmed/32148968 http://dx.doi.org/10.1155/2020/6562896 |
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