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Identification of RNPC3 as a novel JAK2 fusion partner gene in B‐acute lymphoblastic leukemia refractory to combination therapy including ruxolitinib

BACKGROUND: Hematopoietic neoplasms with chromosomal translocations involving JAK2 are rare, and most of them show myeloproliferative neoplasm‐associated features, followed by B‐acute lymphoblastic leukemia (B‐ALL). De novo B‐ALL cases with JAK2 rearrangements are suggested to be appropriately consi...

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Detalles Bibliográficos
Autores principales: Chen, Xue, Wang, Fang, Zhang, Yang, Ma, Xiaoli, Liu, Mingyue, Cao, Panxiang, Zhou, Lin, Wang, Lan, Zhang, Xian, Wang, Tong, Liu, Hongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057088/
https://www.ncbi.nlm.nih.gov/pubmed/31885183
http://dx.doi.org/10.1002/mgg3.1110