METTL3 Facilitates Oral Squamous Cell Carcinoma Tumorigenesis by Enhancing c-Myc Stability via YTHDF1-Mediated m(6)A Modification

N(6)-Methyladenosine (m(6)A) is the most common internal modification of eukaryotic messenger RNA (mRNA) that occurred on the N(6) nitrogen of adenosine. However, the roles of m(6)A in oral squamous cell carcinoma (OSCC) are still elusive. Here, we investigate the function and mechanism of methyltra...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Cui, Yameng, Liu, Lina, Ma, Xiaozhou, Qi, Xiaoqian, Wang, Yue, Liu, Zihao, Ma, Shiqing, Liu, Jingwen, Wu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057159/
https://www.ncbi.nlm.nih.gov/pubmed/32145676
http://dx.doi.org/10.1016/j.omtn.2020.01.033

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