Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4(+) T Cell Engulfment Process

CD4(+) T cells play critical roles in directing immunity, both as T helper and as regulatory T (Treg) cells. Here, we demonstrate that hepatocytes can modulate T cell populations through engulfment of live CD4(+) lymphocytes. We term this phenomenon enclysis to reflect the specific enclosure of CD4(...

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Detalles Bibliográficos
Autores principales: Davies, Scott P., Reynolds, Gary M., Wilkinson, Alex L., Li, Xiaoyan, Rose, Rebecca, Leekha, Maanav, Liu, Yuxin S., Gandhi, Ratnam, Buckroyd, Emma, Grove, Joe, Barnes, Nicholas M., May, Robin C., Hubscher, Stefan G., Adams, David H., Huang, Yuehua, Qureshi, Omar, Stamataki, Zania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057271/
https://www.ncbi.nlm.nih.gov/pubmed/31693899
http://dx.doi.org/10.1016/j.celrep.2019.09.068

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