Regulatory T-cell depletion in the setting of autologous stem cell transplantation for multiple myeloma: pilot study

BACKGROUND: Progression after high-dose melphalan with autologous stem cell transplantation (ASCT) in multiple myeloma (MM) may be due in part to immune dysfunction. Regulatory T (Treg) cells reconstitute rapidly after ASCT and inhibit immune responses against myeloma cells. METHODS: We performed a...

Descripción completa

Detalles Bibliográficos
Autores principales: Derman, Benjamin A, Zha, Yuanyuan, Zimmerman, Todd M, Malloy, Rebecca, Jakubowiak, Andrzej, Bishop, Michael R, Kline, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057425/
https://www.ncbi.nlm.nih.gov/pubmed/31940591
http://dx.doi.org/10.1136/jitc-2019-000286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057425/
https://www.ncbi.nlm.nih.gov/pubmed/31940591
http://dx.doi.org/10.1136/jitc-2019-000286

Ejemplares similares