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Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis

BACKGROUND: Peritoneal carcinomatosis is a hallmark of advanced peritoneal tumor progression, particularly for tubal/ovarian high-grade serous carcinomas (HGSCs). Patients with peritoneal carcinomatosis have poor survival rates and are difficult to treat clinically due to widespread tumor disseminat...

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Detalles Bibliográficos
Autores principales: Tseng, Ssu-Hsueh, Park, Sung-Taek, Lam, Brandon, Tsai, Ya-Chea, Cheng, Max A, Farmer, Emily, Xing, Deyin, Hung, Chien-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057437/
https://www.ncbi.nlm.nih.gov/pubmed/32111730
http://dx.doi.org/10.1136/jitc-2019-000480