CCL5-armed oncolytic virus augments CCR5-engineered NK cell infiltration and antitumor efficiency

BACKGROUND: Natural killer (NK) cells have potent antitumor activities. Nevertheless, adoptive transfer therapy of NK cells has gained very limited success in patients with solid tumors as most infused NK cells remain circulating in the peripheral blood instead of entering tumor sites. Chemokines an...

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Detalles Bibliográficos
Autores principales: Li, Feng, Sheng, Yuqiao, Hou, Weizhou, Sampath, Padma, Byrd, Daniel, Thorne, Stephen, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057442/
https://www.ncbi.nlm.nih.gov/pubmed/32098828
http://dx.doi.org/10.1136/jitc-2019-000131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057442/
https://www.ncbi.nlm.nih.gov/pubmed/32098828
http://dx.doi.org/10.1136/jitc-2019-000131

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