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Functional activities of beta-glucans in the prevention or treatment of cervical cancer

Cervical cancer is the fourth-ranked cancer in the world and is associated with a large number of deaths annually. Chemotherapy and radiotherapy are known as the common therapeutic approaches in the treatment of cervical cancer, but because of their side effects and toxicity, researchers are trying...

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Autores principales: Chaichian, Shahla, Moazzami, Bahram, Sadoughi, Fatemeh, Haddad Kashani, Hamed, Zaroudi, Marsa, Asemi, Zatollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057557/
https://www.ncbi.nlm.nih.gov/pubmed/32138756
http://dx.doi.org/10.1186/s13048-020-00626-7
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author Chaichian, Shahla
Moazzami, Bahram
Sadoughi, Fatemeh
Haddad Kashani, Hamed
Zaroudi, Marsa
Asemi, Zatollah
author_facet Chaichian, Shahla
Moazzami, Bahram
Sadoughi, Fatemeh
Haddad Kashani, Hamed
Zaroudi, Marsa
Asemi, Zatollah
author_sort Chaichian, Shahla
collection PubMed
description Cervical cancer is the fourth-ranked cancer in the world and is associated with a large number of deaths annually. Chemotherapy and radiotherapy are known as the common therapeutic approaches in the treatment of cervical cancer, but because of their side effects and toxicity, researchers are trying to discovery alternative therapies. Beta-glucans, a group of glucose polymers that are derived from the cell wall of fungi, bacteria, and etc. it has been showed that beta-glucans have some anti-cancer properties which due to their impacts on adaptive and innate immunity. Along to these impacts, these molecules could be used as drug carriers. In this regard, the application of beta-glucans is a promising therapeutic option for the cancer prevention and treatment especially for cervical cancer. Herein, we have summarized the therapeutic potential of beta-glucans alone or as adjuvant therapy in the treatment of cervical cancer. Moreover, we highlighted beta-glucans as drug carriers for preventive and therapeutic purposes.
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spelling pubmed-70575572020-03-10 Functional activities of beta-glucans in the prevention or treatment of cervical cancer Chaichian, Shahla Moazzami, Bahram Sadoughi, Fatemeh Haddad Kashani, Hamed Zaroudi, Marsa Asemi, Zatollah J Ovarian Res Review Cervical cancer is the fourth-ranked cancer in the world and is associated with a large number of deaths annually. Chemotherapy and radiotherapy are known as the common therapeutic approaches in the treatment of cervical cancer, but because of their side effects and toxicity, researchers are trying to discovery alternative therapies. Beta-glucans, a group of glucose polymers that are derived from the cell wall of fungi, bacteria, and etc. it has been showed that beta-glucans have some anti-cancer properties which due to their impacts on adaptive and innate immunity. Along to these impacts, these molecules could be used as drug carriers. In this regard, the application of beta-glucans is a promising therapeutic option for the cancer prevention and treatment especially for cervical cancer. Herein, we have summarized the therapeutic potential of beta-glucans alone or as adjuvant therapy in the treatment of cervical cancer. Moreover, we highlighted beta-glucans as drug carriers for preventive and therapeutic purposes. BioMed Central 2020-03-05 /pmc/articles/PMC7057557/ /pubmed/32138756 http://dx.doi.org/10.1186/s13048-020-00626-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Chaichian, Shahla
Moazzami, Bahram
Sadoughi, Fatemeh
Haddad Kashani, Hamed
Zaroudi, Marsa
Asemi, Zatollah
Functional activities of beta-glucans in the prevention or treatment of cervical cancer
title Functional activities of beta-glucans in the prevention or treatment of cervical cancer
title_full Functional activities of beta-glucans in the prevention or treatment of cervical cancer
title_fullStr Functional activities of beta-glucans in the prevention or treatment of cervical cancer
title_full_unstemmed Functional activities of beta-glucans in the prevention or treatment of cervical cancer
title_short Functional activities of beta-glucans in the prevention or treatment of cervical cancer
title_sort functional activities of beta-glucans in the prevention or treatment of cervical cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057557/
https://www.ncbi.nlm.nih.gov/pubmed/32138756
http://dx.doi.org/10.1186/s13048-020-00626-7
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