Glutaminase-1 (GLS1) inhibition limits metastatic progression in osteosarcoma

BACKGROUND: Osteosarcoma (OS) is a malignant bone tumor that often develops during the period of rapid growth associated with adolescence. Despite successful primary tumor control accompanied by adjuvant chemotherapy, death from pulmonary metastases occurs in approximately 30% of patients within 5 y...

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Detalles Bibliográficos
Autores principales: Ren, L., Ruiz-Rodado, V., Dowdy, T., Huang, S., Issaq, S. H., Beck, J., Wang, H., Tran Hoang, C., Lita, A., Larion, M., LeBlanc, A. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057558/
https://www.ncbi.nlm.nih.gov/pubmed/32158544
http://dx.doi.org/10.1186/s40170-020-0209-8

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